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The histochemistry of the dehydrogenase systems in the aortae of rabbits with experimental atherosclerosis

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Zusammenfassung

In Aorten von Kaninchen mit experimenteller Atherosklerose wurden die folgenden Dehydrogenasen untersucht: DPN-Diaphorase, Lactat- und Malat-Dehydrogenase, TPN-Diaphorase, Succinat-, Glucoso-6-phosphat-und Glutamat-Dehydrogenase. Die Aktivität der fünf erstgenannten war in den Endothelien, Makrophagen (Lipophagen) und Fibrozyten der verdickten Intima und kleiner atherosklerotischer Beete deutlich erhöht. Die Befunde stehen im Einklang mit der Ansicht, dass die Stoffwechselaktivität der Intima am Anfang der experimentellen Atherogenesis erhöht ist.

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References

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Authors and Affiliations

  1. Embryological Institute, Medical Faculty, Charles University and Research Institute for Endocrinology, Prague, Czech Republic

    Z. Lojda & V. Felt

Authors
  1. Z. Lojda
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  2. V. Felt
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Additional information

Further work on the dehydrogenase systems in plaques in rabbit, rats, and humans is in progress and will be reported in detail elsewhere.

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Lojda, Z., Felt, V. The histochemistry of the dehydrogenase systems in the aortae of rabbits with experimental atherosclerosis. Experientia 16, 514–515 (1960). https://doi.org/10.1007/BF02158376

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  • DOI: https://doi.org/10.1007/BF02158376

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