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Enzymatic conversion of metanephrine to normetanephrine

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Zusammenfassung

In der Mikrosomen-Fraktion der Leber von Kaninchen, Ratte und Meerschweinchen wurde ein Ferment gefunden, welches Metanephrin zu Normetanephrin unter Formaldehydbildung N-demethylieren kann.

Nach Verabreichung von markiertem Epinephrin und Metanephrin konnten bei der Ratte keine Anhaltspunkte für die Ausscheidung von Normetanephrin gefunden werden.

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References

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Authors and Affiliations

  1. Laboratory of Clinical Science, National Institute of Mental Health, Bethesda, Maryland

    J. Axelrod

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  1. J. Axelrod
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Axelrod, J. Enzymatic conversion of metanephrine to normetanephrine. Experientia 16, 502–503 (1960). https://doi.org/10.1007/BF02158363

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  • DOI: https://doi.org/10.1007/BF02158363

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