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Mikrobiologischer Nachweis von Antibiotika auf Dünnschichtchromatogrammen

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Summary

Numerous tetracyclines, penicillins and rifomycins on thin layer chromatograms may be detected by microbiological development withSarcina lutea andBacillus subtilis in the presence of triphenyltetrazolium salts. This technique is exceptionally sensitive (0.01–0.1γ), the inhibition zones being much sharper than on paper chromatograms.

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References

  1. B. J. R. Nicolaus, C. Coronelli undA. Binaghi, Il Farmaco16, 349 (1961).

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Authors and Affiliations

  1. Laboratori di Ricerca della Lepetit S.p.A. Milano, Italien

    B. J. R. Nicolaus, C. Coronelli & A. Binaghi

Authors
  1. B. J. R. Nicolaus
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  2. C. Coronelli
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  3. A. Binaghi
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Nicolaus, B.J.R., Coronelli, C. & Binaghi, A. Mikrobiologischer Nachweis von Antibiotika auf Dünnschichtchromatogrammen. Experientia 17, 473–474 (1961). https://doi.org/10.1007/BF02158302

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  • DOI: https://doi.org/10.1007/BF02158302

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