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Loss of tryptophan pyrrolase cofactor from liver cytoplasmic structures of 3′-methyl-4-dimethylaminoazobenzene fed rats

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Résumé

L'ingestion du cancérogène 3-méthyl-4-diméthylaminoazobenzène pendant 40 jours inhibe fortement l'induction de la tryptophane pyrrolase du foie des rats causée par leL-tryptophane ou bien l'hydrocortisone. Les auteurs montrent que cet effet est dû à la perte du cofacteur de la tryptophane pyrrolase des mitochondries et des microsomes des animaux soumis au régime alimentaire cancérogène.

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Authors and Affiliations

  1. Department of Biochemistry, Higher Medical Institute, Sofia, Bulgaria

    A. A. Hadjiolov & M. D. Dabeva

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  1. A. A. Hadjiolov
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  2. M. D. Dabeva
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Hadjiolov, A.A., Dabeva, M.D. Loss of tryptophan pyrrolase cofactor from liver cytoplasmic structures of 3′-methyl-4-dimethylaminoazobenzene fed rats. Experientia 17, 452–453 (1961). https://doi.org/10.1007/BF02158283

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