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Conversion of 17α-hydroxypregnenolone to cortisol

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Zusammenfassung

Nebennierenschnitte von Ratten, Meerschweinchen und Menschen synthetisierten 17α-Hydroxyprogesteron, 11-Deoxycortisol und Cortisol aus 17α-Hydroxypregnenolon. Diese Verbindung, als Ausgangsprodukt für die Cortisolsynthese, ist ebenso wirksam wie pregnenolon. Die Umwandlung von 17α-Hydroxypregnenolon in Dehydroepiandrosteron verläuft weniger vollkommen als zu 17α-Hydroxycorticoiden.

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Author notes

  1. M. B. Lipsett

    Present address: National Cancer Institute Bethesda, Md., USA

Authors and Affiliations

  1. Department of Endocrinology, Karolinska Hospital, Stockholm, Sweden

    M. B. Lipsett & B. Hökfelt

Authors
  1. M. B. Lipsett
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  2. B. Hökfelt
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Lipsett, M.B., Hökfelt, B. Conversion of 17α-hydroxypregnenolone to cortisol. Experientia 17, 449–450 (1961). https://doi.org/10.1007/BF02158281

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