Zusammenfassung
Phenylethylamin, 3-Methoxy-dopamin undp-Hydroxyamphetamin werden durch Dopamin-β-oxidase in die entsprechendeβ-Hydroxy-Verbindung umgewandelt.
References
The enzyme was prepared by the method ofE. Y. Levin et al.3 but the purification on calcium phosphate gel was omitted.
E. Y. Levin et al., J. biol. Chem.235, 2080 (1960).
The 3-methoxy-H3 dopamine was prepared enzymatically by the method ofJ. Axelrod et al.5.
J. Axelrod et al., J. biol. Chem.233, 697 (1958).
M. Goldstein et al., Proc. Soc. exp. Biol. Med.103, 137 (1960).
M. Goldstein et al., to be published.
M. Goldstein et al., Biochem. Pharmacol., in press.
S. Senoh et al., J. Amer. chem. Soc.81, 6236 (1959).
I. E. Bush, Biochem. J.50, 370 (1951).
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This work was supported by grants from the National Institutes of Health.
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Goldstein, M., Contrera, J.F. Studies on enzymicβ-hydroxylation of phenylethyl amines. Experientia 17, 447–448 (1961). https://doi.org/10.1007/BF02158279
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DOI: https://doi.org/10.1007/BF02158279