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Substituierte t-Hexylamine als neuer Typ hypotensiv wirksamer Verbindungen

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Summary

A series of primary, secondary, and tertiary 2,2,3-trimethylbutylamines-(3) and their salts substituted in position 3 with a methyl, ethyl,n-butyl, phenyl, and benzyl group has been prepared. One member of the series, N,N,2,2,3-pentamethylbutylamine-(3) (Penbutamine) as well as the corresponding amino and methylamino derivatives were compared with other compounds of a similar type as regards their ganglioplegic and hypotensive effect. The tested compound revealed a high degree of activity in both the above mentioned directions.

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References

  1. Z. J. Vejdělek undM. Protiva, Chem. listy52, 2370 (1958).

    Google Scholar 

  2. M. Protiva, M. Rajšner, V. Trčka, M. Vaněček undZ. J. Vejdělek, Exper.15, 54 (1959).

    CAS  Google Scholar 

  3. Z. J. Vejdělek, M. Rajšner undM. Protiva, Collection, im Druck.

  4. A. Spinks undE. H. P. Young, Nature181, 1397 (1958).

    Article  CAS  Google Scholar 

  5. S. J. Corne undN. D. Edge, Brit. J. Pharmacol.13, 339 (1958).

    CAS  PubMed  PubMed Central  Google Scholar 

  6. A. Spinks, E. H. P. Young, J. A. Farrington undD. Dunlop, Brit. J. Pharmacol.13, 501 (1958).

    CAS  PubMed  PubMed Central  Google Scholar 

  7. J. J. Ritter undP. P. Minieri, J. Amer. chem. Soc.70, 4045 (1948).

    Article  CAS  Google Scholar 

  8. J. J. Ritter undJ. Kalish, J. Amer. chem. Soc.70, 4048 (1948).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Forschungsinstitut für Pharmazie und Biochemie, Prag

    Z. J. Vejdělek & V. Trčka

Authors
  1. Z. J. Vejdělek
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  2. V. Trčka
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Additional information

11. Mitteilung « Ganglioplegica », 10. Mitteilung siehe Collection, im Druck.

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Vejdělek, Z.J., Trčka, V. Substituierte t-Hexylamine als neuer Typ hypotensiv wirksamer Verbindungen. Experientia 15, 215–216 (1959). https://doi.org/10.1007/BF02158110

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  • DOI: https://doi.org/10.1007/BF02158110

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