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Abschwächung der Noradrenalin-Wirkung auf die isolierte Aorta bei Hemmung der Monoaminoxydase

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Summary

Twenty hours after pretreatment of rabbits with the monoamine oxidase inhibitor N2-isopropyl-isonicotinic acid hydrazide (IIH) the norepinephrine induced contraction of the isolated aorta was significantly reduced; the 5-hydroxytryptamine sensitivity could not be changed significantly. Isonicotinic acid hydrazide (INH), a weak monoamine oxidase inhibitor, had no significant effect on the norepinephrine and 5-hydroxytryptamine sensitivity of the aorta.

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Authors and Affiliations

  1. Abteilung für experimentelle Medizin der F. Hoffmann-La Roche & Co. AG., Basel

    H. P. Bächtold & A. Pletscher

Authors
  1. H. P. Bächtold
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  2. A. Pletscher
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Bächtold, H.P., Pletscher, A. Abschwächung der Noradrenalin-Wirkung auf die isolierte Aorta bei Hemmung der Monoaminoxydase. Experientia 15, 265–267 (1959). https://doi.org/10.1007/BF02158075

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  • DOI: https://doi.org/10.1007/BF02158075

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