Summary
Ultrastructural changes in spleen and liver in a case ofMorbus Gaucher andNiemann-Pick are discussed.
The results are: (1) The Ultrastructure shows a distinct differentiation between the two diseases. (2) It seems that storage begins in mitochondria. (3) In the case ofMorbus Niemann-Pick, all Mitochondria of storage cells show an abnormal ultrastructure (diminuation in size, increased osmiophilia, disorder in the arrangement of cristae and membranes).
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Roos, B., Cottier, H. & Rossi, E. Elektronenoptische Beobachtungen bei Speicherkrankheiten. Experientia 17, 430 (1961). https://doi.org/10.1007/BF02157992
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DOI: https://doi.org/10.1007/BF02157992