Skip to main content
SpringerLink
Log in

An antagonism between 3–4 dioxyphenylalanine (DOPA) and 5-hydroxytryptophan (5-HTP)

  • Kurze Mitteilungen
  • Published:
Experientia Aims and scope Submit manuscript

Riassunto

Recentemente è stata formulata l'ipotesi che la 5-idrossitriptamina e la noradrenalina agiscano come mediatori a livello del S.N.C. I risultati ottenuti dall'A. dimostrano che la diossifenilalanina può antagonizzare il potenziamento della narcosi barbiturica indotto dal 5-idrossitriptafano.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. W. R. Hess,Das Zwischenhirn (Benno Schwabe and Co., Basle 1954).

    Google Scholar 

  2. B. B. Brodie andP. A. Shore, Ann. N. Y. Acad. Sci.66, 631 (1957).

    Article  CAS  PubMed  Google Scholar 

  3. R. Jaques, H. J. Bein, andR. Meier, Helv. physiol. Acta14, 269 (1956).

    CAS  Google Scholar 

  4. S. Garattini andL. Valzelli, Boll. Soc. ital. Biol. sper.32, 288 (1956).

    CAS  PubMed  Google Scholar 

  5. S. Garattini andL. Valzelli, Boll. Soc. ital. Biol. sper.32, 292 (1956).

    CAS  PubMed  Google Scholar 

  6. P. Gordon, F. J. Naddy, andM. A. Lipton, Science128, 531 (1958).

    Article  CAS  PubMed  Google Scholar 

  7. P. Fornaroli andM. Koller, Il Farmaco, ed. sci.9, 546 (1954).

    CAS  Google Scholar 

  8. F. N. Fastier, Exper.12, 351 (1956).

    CAS  Google Scholar 

  9. A. Yuwiber, E. Geller, andS. Eduson, Arch. Biochem. Biophys.80, 162 (1958).

    Google Scholar 

  10. It should be also recalled that a potentiation between serotonin and norepinephrine has been observed11.

  11. R. Meier, T. Tripod, andE. Wirz, Arch. int. Pharmacodyn109, 55 (1957).

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Istituto di Farmacologia e di Terapia, Università degli Studi, Milano

    R. Kato

Authors
  1. R. Kato
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Research fellow from Keio University, Tokyo (Japan).

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kato, R. An antagonism between 3–4 dioxyphenylalanine (DOPA) and 5-hydroxytryptophan (5-HTP). Experientia 15, 424–425 (1959). https://doi.org/10.1007/BF02157692

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02157692

Keywords

Search

Navigation