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A view of progress in the chemistry of indole alkaloids

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Zusammenfassung

Neuere Erkenntnisse der theoretischen Chemie, Entwicklungen der chemischen Experimentierkunst und neue und verbesserte physikalische Instrumentation haben die Entwicklung der Indolalkaloidchemie im letzten Dezennium entscheidend gefördert. Die erfolgreiche Konstitutionsermittlung einer Reihe längst bekannter Indolalkaloide wurde dadurch ermöglicht. Ihre Konstitution sowie die Strukturen unlängst isolierter Indolbasen lassen auf eine grosse Mannigfaltigkeit im strukturellen Bau der Indolalkaloide schliessen. Die Biosynthese der Indolalkaloide wird kurz diskutiert, zusammen mit Kommentaren über den Ursprung des Rings E und der Carboxylgruppe in den Yohimbinen.

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Authors and Affiliations

  1. Research Department, CIBA Pharmaceutical Products Inc., Summit, N. J.

    W. I. Taylor

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  1. E. Schlittler
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  2. W. I. Taylor
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Additional information

This essay reflects the authors' approach to this subject. Only the major theme is developed but certain ideas buried in text may act as catalysts for further thought.

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Schlittler, E., Taylor, W.I. A view of progress in the chemistry of indole alkaloids. Experientia 16, 244–248 (1960). https://doi.org/10.1007/BF02157662

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