Experientia

, Volume 13, Issue 3, pp 122–123 | Cite as

L'action du dithizone sur la rétine du lapin Etude électrophysiologique

  • J. Babel
  • B. Ziv
Kurze Mitteilungen

Summary

Dithizone provokes chorio-retinal lesions in the rabbit, visible ophthalmoscopally after 12 h and microscopally after 8 h. The ERG reveals much earlier alterations, theb wave diminishes rapidly and the ERG is abolished in 3 to 4 h. In the cases where no durable lesions are noted, the ERG is nevertheless pathological, theb wave being diminished 40 to 70% of its initial value during the first day, but becoming normal once again even if a permanent diabetes results. These anomalies of the ERG are related to acute hypoglycaemia and enzymatic blockage.

References

  1. 1.
    U. Butturini, A. Grignolo etA. Baronchelli, G. Clin. med.34, 1253 (1953).PubMedGoogle Scholar

Copyright information

© Birkhäuser Verlag 1957

Authors and Affiliations

  • J. Babel
    • 1
  • B. Ziv
    • 1
  1. 1.Clinique Ophtalmologique de l'Université de GenèveSwitzerland

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