Eigenschaften der Adenovirus-Hämagglutinine
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Adenovirus hemagglutinins were classified into five groups designated as A to E according to differences in heat stability, sensitivity to trypsin treatment or to trypsin plus subsequent heating, adsorption of hemagglutinin and infectious virus to red cells and separation of hemagglutinin from infectious virus by ultracentrifugation. These properties are summarized in Table 12. Hemagglutination by A hemagglutinin is demonstrable only in the presence of heterologous adenovirus immune serum, probably of all serotypes. Hemagglutinin A may modify red cell receptors in absence of heterologous serum; these receptors appear to be different from those involved in hemagglutination by myxoviruses. The mechanism of hemagglutination by the various hemagglutinins is discussed.
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- Bell, S. D., jr.,T. R. Rota andD. E. McComb: Adenovirusses isolated from Saudi Arabia. III. Six new serotypes. Amer. J. trop. Med. Hyg.9, 523–526 (1960).Google Scholar
- Buckland, F. E.: Impairment of viral haemagglutination of red cells after treatment with formalin. Nature (Lond.)183, 1276 (1959).Google Scholar
- —: Inactivation of virus haemagglutinins by para-chloromercuribenzoic acid. Nature (Lond.)188, 768 (1960).Google Scholar
- —,A. C. Allison andC. P. Farthing: Study of adenovirus antigens by immunoelectrophoresis. Nature (Lond.)183, 895–896 (1959).Google Scholar
- —,S. Baron andJ. A. Bell: Four newly recognized adenoviruses. Proc. Soc. exp. Biol. (N. Y.)107, 434–437 (1961).Google Scholar
- Rowe, W. P., J. W. Hartley andR. J. Huebner: Serotype composition of the adenovirus group. Proc. Soc. exp. Biol. (N. Y.)97, 465–470 (1958).Google Scholar
- Wigand, R., u.H. Bauer: Grundlegende Unterschiede in den Eigenschaften der Hämagglutinine verschiedener Adenovirustypen. Zbl. Bakt., I. Abt. Orig.184, 60–65 (1962).Google Scholar
- Zhdanov, V. M., andL. B. Mekler: Correlation between the surface structure of viruses and latency. Nature (Lond.)195, 924 (1962).Google Scholar
- Zuschek, F.: Studies of the hemagglutinins of type 3, 4 and 7 adenovirus. Proc. Soc. exp. Biol. (N.Y.)107, 27–30 (1961).Google Scholar