Eigenschaften der Adenovirus-Hämagglutinine
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Adenovirus hemagglutinins were classified into five groups designated as A to E according to differences in heat stability, sensitivity to trypsin treatment or to trypsin plus subsequent heating, adsorption of hemagglutinin and infectious virus to red cells and separation of hemagglutinin from infectious virus by ultracentrifugation. These properties are summarized in Table 12. Hemagglutination by A hemagglutinin is demonstrable only in the presence of heterologous adenovirus immune serum, probably of all serotypes. Hemagglutinin A may modify red cell receptors in absence of heterologous serum; these receptors appear to be different from those involved in hemagglutination by myxoviruses. The mechanism of hemagglutination by the various hemagglutinins is discussed.
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