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Differences in the dexoxyribonucleoprotein complex of normal and leukemic human lymphocytes

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Riassunto

Gli autori hanno determinato con metodo citofotometrico nel visibile il contenuto di acido desossiribonucleico (DNA) e di proteina istonica nei linfociti di 4 soggetti normali e di 4 pazienti affetti da leucosi linfatica.

I valori del DNA sono apparsi uguali nelle cellule normali e in quelle leucemiche, i valori dell'istone sono risultati in queste ultime superiori alla norma, onde il rapporto DNA/istone risulta essere nei linfociti leucemici inferiore a quello dei linfociti normali.

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Perugini, S., Torelli, U. & Soldati, M. Differences in the dexoxyribonucleoprotein complex of normal and leukemic human lymphocytes. Experientia 13, 441–442 (1957). https://doi.org/10.1007/BF02157239

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