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The uptake of pyrithiamine by cerebral tissue

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Riassunto

Il livello di PT che si instaura nel fegato, rene e muscolo di ratti iniettati con 1 mg di PT in peritoneo e tenuti a dieta carente di T diminuisce continuamente nel giro di 12 giorni, mentre aumenta gradatamente nel cervello. Ciò può spiegare la particolare efficacia della PT nell'abbassare selettivamente il contenuto in T totale nel tessuto cerebrale.

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Rindi, G., Perri, V. & De Caro, L. The uptake of pyrithiamine by cerebral tissue. Experientia 17, 546–547 (1961). https://doi.org/10.1007/BF02156413

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