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Separation and identification of the degradation products of purines and nucleic acids on acid hydrolysis by circular paper chromatography

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Zusammenfassung

Die Degradationsprodukte, die sich bei der Hydrolyse der Purine, der Pyrimidine und der Nukleinsäuren bilden, werden mittels runder Filterpapierscheiben chromatographisch untersucht. Adenine, Nukleinsäuren und Adeninverbindungen zeigen bei einer Säurehydrolyse ausser einem Band, das den Platz des Glycin einnimmt, noch ein weiteres Band. Dieses Band ist versuchsweise als 4(5)-amino-5(4)-imidazol Carboxamidin charakterisiert worden. Die Bedeutung dieser Ergebnisse für die quantitative Analyse der Nukleinsäuren und Adeninverbindungen wird in der vorliegenden Arbeit erörtert.

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References

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Authors and Affiliations

  1. Departement of Biochemistry, Indian Institute of Science, Bangalore 3, India

    K. V. Giri, P. R. Krishnaswamy, G. D. Kalyankar & P. L. Narasimha Rao

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  1. K. V. Giri
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  2. P. R. Krishnaswamy
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  3. G. D. Kalyankar
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  4. P. L. Narasimha Rao
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Giri, K.V., Krishnaswamy, P.R., Kalyankar, G.D. et al. Separation and identification of the degradation products of purines and nucleic acids on acid hydrolysis by circular paper chromatography. Experientia 9, 296–297 (1953). https://doi.org/10.1007/BF02156020

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