Summary
Blood deprived of the plasma and blood cells cholinesterases by DFP was transfused into a normal dog after total bleeding. The experiments showed that although the blood cholinesterases were at a very low level in the transfused animals, no so-called “cholinergic reactions” could be observed. However, the blood cholinesterases regenerate very fast from the tissue cholinesterases.
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References
C. Heymans, R. Pannier, R. Verbeke etJ. Jacob, Arch intern. Pharmacodyn.72, 405 (1946);74, 233 (1947) avec bibliogr.
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Heymans, C., Casier, H. Sur la régénération des cholinestérases du sang. Experientia 4, 75 (1948). https://doi.org/10.1007/BF02155993
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DOI: https://doi.org/10.1007/BF02155993