Skip to main content
SpringerLink
Log in

Traitement de la syphilis expérimentale du Lapin par la pénicilline en suspension dans l'huile

  • Kurze Mitteilungen
  • Published:
Experientia Aims and scope Submit manuscript

Summary

When suspended in beeswax-peanut oil according toRomansky andRittman, a total amount of 50,000 Oxford units of C. S. C. penicillin (Commercial Solvents Corporation U.S.A.) pro kg., covering 8 intramuscular injections with intervals of one day, apparently sufficed to cure of syphilis (Ghent strain) rabbits infected into both testicles for two months to one year. The criteria of healing were applied 4 to 7 months after the end of the treatment and consisted in the transfer of the popliteal lymph nodes and other organs and in a second inoculation with the homologous strain. Unknown factors must be considered to explain the different results of the sole penicillinotherapy of syphilis observed in rabbits and in man.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. M. J. Romansky etG. E. Rittman, Science,100, 196 (1944); Bull. U.S. Army med. Dep., No. 81, p. 43 (1944); New Engl. J. Med.,233, 577 (1945);M. J. Romansky, R. J. Murphy etG. E. Rittman, J. Am. med. Ass.128, 404 (1945).

    Article  CAS  Google Scholar 

  2. M. J. Romansky etC. R. Rein, J. Am. med. Ass.132, 847 (1946).

    Article  CAS  Google Scholar 

  3. A. Bessemans etA. Denoo, Bull. Acad. roy, Méd. Belgique. No 8, p. 530 (1941); Ann. Inst. Pasteur,68, 294 (1942); Arch. physic. Med.27, 547 (1946).

  4. P. Gastinel, Bull. Acad. Méd. (Paris),129, 587 (1945).

    Google Scholar 

  5. P. A. O'Leary etR. R. Kierland, J. Am. med. Ass.132, 430 (1946).

    Article  CAS  Google Scholar 

  6. J. Yampolski etA. Heyman, J. Am. med. Ass.132, 368 (1946).

    Article  Google Scholar 

  7. Cl. Huriez etM. Desurmont, Presse méd., N0 35, p. 401 (1947)

  8. Therapeutic Notes (Parke, Davis et Co.) p. 87, avril 1946-etc.

Download references

Author information

Authors and Affiliations

  1. Institut d'hygiène et de bactériologie de l'Université de l'Etat à Gand, Belgique

    A. Bessemans, R. Derom, P. Doussy & P. Derom

Authors
  1. A. Bessemans
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. R. Derom
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. P. Doussy
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. P. Derom
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bessemans, A., Derom, R., Doussy, P. et al. Traitement de la syphilis expérimentale du Lapin par la pénicilline en suspension dans l'huile. Experientia 3, 376–377 (1947). https://doi.org/10.1007/BF02154727

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02154727

Search

Navigation