Summary
The bromination ofΔ 4-3-keto-steroids with the aid of N-bromo-succinimide takes place in 6-position, that is in allyl-position and not inα-position to the keto group. By splitting off hydrogen bromide from these 6-bromo-compounds,Δ 4;6-3-keto-steroids are obtained in known manner.
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53. Mitteilung der Reihe «Über Steroide» (52. Mitt. s. Helv. chim. acta29, 1231 (1946).
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Meystre, C., Wettstein, A. Einwirkung von N-Brom-succinimid aufΔ4-3-Keto-steroide. Experientia 2, 408–409 (1946). https://doi.org/10.1007/BF02154217
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DOI: https://doi.org/10.1007/BF02154217