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New 1,2-disubstituted benzimidazoles with high inhibiting effects on poliovirus Replication

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  • Chimica. Biochimica
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Zusammenfassung

1-Phenyl- und 1-β-Methylpropyl-2-(α-oxy-benzyl)-benzimidazol setzen die Vermehrung des Poliovirus der Arten 1, 2 und 3 in der Gewebekulturzelle stark herab. Die Hemmwirkungen und die Beeinflussung der Toxizitätsverhältnisse der 1-Phenyl-Derivate sind alle grösser, als die der früher untersuchten Benzimidazolene.

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References

  1. D. G. O'Sullivan andA. K. Wallis, Nature198, 1270 (1963).

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  2. D. G. O'Sullivan, D. Pantic andA. K. Wallis, Nature203, 433 (1964).

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  5. D. G. O'Sullivan andA. K. Wallis, unpublished work.

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Authors and Affiliations

  1. Courtauld Institute of Biochemistry, Middlesex Hospital Medical School, W.1., London, England

    D. G. O'Sullivan, Danica Pantic & A. K. Wallis

Authors
  1. D. G. O'Sullivan
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  2. Danica Pantic
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  3. A. K. Wallis
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Additional information

The research is supported by the National Fund for Research into Poliomyelitis and other Crippling Diseases.

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O'Sullivan, D.G., Pantic, D. & Wallis, A.K. New 1,2-disubstituted benzimidazoles with high inhibiting effects on poliovirus Replication. Experientia 23, 704–706 (1967). https://doi.org/10.1007/BF02154123

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  • DOI: https://doi.org/10.1007/BF02154123

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