Summary
Antibodies produced following injections of a proteinic antigen emulsified in Freund's adjuvant were studied by the passive hemagglutination test in some lots of WCF rats, varying in age. It is shown by treating sera with mercaptoethanol that older animals produce less 7 S antibodies than younger ones, and that, despite this difference, rats remain able to elaborate seric antibodies at relatively high rates during their senescence period.
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Goullet, P., Gaillard, C. & de Jeannequin, O. Production d'anticorps 7 S et 19 S chez des Rats d'âge différent. Experientia 24, 601–603 (1968). https://doi.org/10.1007/BF02153799
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DOI: https://doi.org/10.1007/BF02153799