Silicone oil (1000 and 12500 cs) and fluorosilicone oil (1000 and 10000 cs) were dyed red and injected into a gas-created space in the vitreous cavity of 51 rabbit eyes. Later the oils were removed from the vitreous cavity either by lavage with balanced salt solution (group 1, 27 eyes) or by injecting a sodium hyaluronate solution, followed by lavage with balanced salt solution (group 2, 24 eyes). The average amount of oil retained in the vitreous cavity in group 1 was 0.0675 ml, and occasionally a large amount of oil was found (more than 0.1 ml in 30% of eyes). The average amount of oil retained in group 2 was 0.0114 ml, and no eye retained more than 0.1 ml of oil. The difference between the two groups was statistically significant (p < 0.02), but there was no significant difference in oil retention within either group between the different kinds of oils, or between different viscosities of oil. The data suggest that residual oil can persist in the vitreous cavity despite thorough lavage, and that removal of silicone oil with the use of a sodium hyaluronate solution significantly lowers the risk of a large amount of residual silicone oil that is occasionally seen with conventional removal methods.
Public Health Silicone Viscosity Average Amount Hyaluronate
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
This is a preview of subscription content, log in to check access.
Ando F, Miyake Y, Oshima K, Yamanake A (1986) Temporary use of intraocular silicone oil in the treatment of complicated retinal detachment. Graefe's Arch Clin Exp Ophthalmol 224: 32–33CrossRefGoogle Scholar
Fletcher ME, Peyman GA (1985) A simplified technique for the removal of liquid silicone from vitrectomized eyes. Retina 5: 168–171PubMedGoogle Scholar
Gonvers M (1982) Temporary use of intraocular silicone oil in the treatment of detachment with massive periretinal proliferation. Ophthalmologica 184: 210–218PubMedGoogle Scholar
Gonvers M (1985) Temporary silicone oil tamponade in the management of retinal detachment with proliferative vitreoretinopathy. Am J Ophthalmol 100: 239–245PubMedGoogle Scholar
Haut J, Ullern M, Chermet M, Van Effenterre G (1980) Complications of intraocular injections of silicone combined with vitrectomy. Ophthalmologica 180: 29–35PubMedGoogle Scholar
McCuen BW, Landers MB, Machemer R (1986) The use of silicone oil following failed vitrectomy for retinal detachment with advanced proliferative vitreoretinopathy. Graefe's Arch Clin Exp Ophthalmol 224: 38–39CrossRefGoogle Scholar
Miyamoto K, Refojo MF, Tolentino FI, Fournier GA, Albert DM (1984) Perfluoroether liquid as a long-term vitreous substitute: an experimental study. Retina 4: 264–268PubMedGoogle Scholar
Ni C, Wang WJ, Albert DM, Schepens CL (1983) Intravitreous silicone injection: histopathologic findings in a human eye after 12 years. Arch Ophthalmol 101: 1399–1401PubMedGoogle Scholar
Silicone Study Coordinating Center (1986) Manual of operations, the Silicone Study, revised edn. University of Southern California, Los AngelesGoogle Scholar
Thresher RJ, Ehrenberg M, Machemer R (1984) Gas-mediated vitreous compression: an experimental alternative to mechanized vitrectomy. Graefe's Arch Clin Exp Ophthalmol 221: 192–198CrossRefGoogle Scholar