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Über Milchsäurebildung im Froschmuskel nach Einwirkung einiger krampferzeugender Substanzen

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Summary

Intact frog muscles were perfused with solutions of iodoacetate, allylisothiocyanate, chloroacetone, chloroform, caffeine, mercuric chloride, and chloropicrin. They were made to contract by work and their lactic acid content was determined afterwards. Only iodoacetate inhibited the expected accumulation of lactate in the working muscle. The other investigated substances allowed normal production of lactic acid. Chloropicrin and caffeine caused a small increase. Iodoacetate alone inhibits the production of a true Lundsgaard effect.

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  1. Rudolf Krueger

    Present address: Aus der Pharmakologischen Anstalt der Universität Basel, Switzerland

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    1. Rudolf Krueger
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    Krueger, R. Über Milchsäurebildung im Froschmuskel nach Einwirkung einiger krampferzeugender Substanzen. Experientia 6, 106–107 (1950). https://doi.org/10.1007/BF02153376

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    • DOI: https://doi.org/10.1007/BF02153376

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