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Chromosome aberrations induced by daunomycin in human leucocyte cultures, with the apparent synergistic effect of arginine

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  • Genetica
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Zusammenfassung

Das Antibiotikum und Zytostatikum Daunomycin induziert beträchtliche Chromosomenaberrationen in menschlichen Leukozyten in der Konzentration von 0,02 µg/cm3. Dieser Effekt wird durch Zusatz von Arginin zur Zellkultur wesentlich verstärkt, und die Aberrationen werden auch qualitativ verändert. Es ist nicht bekannt, wie Daunomycin und Arginine aufeinander einwirken.

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Authors and Affiliations

  1. Department of Pediatrics, Ohio State University, The Children's Hospital, 43205, Columbus, Ohio, USA

    B. K. Vig, Stella B. Kontras & L. D. Samuels

Authors
  1. B. K. Vig
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  2. Stella B. Kontras
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  3. L. D. Samuels
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Vig, B.K., Kontras, S.B. & Samuels, L.D. Chromosome aberrations induced by daunomycin in human leucocyte cultures, with the apparent synergistic effect of arginine. Experientia 24, 271–273 (1968). https://doi.org/10.1007/BF02152815

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  • DOI: https://doi.org/10.1007/BF02152815

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