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Influence of diazoxide on regional blood flow in rats

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  • Physiologica
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Zusammenfassung

Der Einfluss von Diazoxid auf die Organdurchblutung der Ratten wurde mittels86Rb untersucht. Eine signifikante Durchblutungssteigerung des Herzens (128% der Kontrollwerte) und der Schilddrüse (139%) konnte bis 150 sec nach i.v. Injektion von 5 mg Diazoxid nachgewiesen werden. Die Durchblutung der Milz hingegen sank rasch auf 45% der Kontrollwerte, wobei nach 150 sec Normalisierung eintrat.

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Authors and Affiliations

  1. Laboratory for Endocrinology and Metabolism, Charles University, Faculty of Medicine, Praha, Czechoslovakia

    J. Kapitola, O. Küchel, O. Schreiberová & I. Jahoda

Authors
  1. J. Kapitola
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  2. O. Küchel
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  3. O. Schreiberová
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  4. I. Jahoda
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Kapitola, J., Küchel, O., Schreiberová, O. et al. Influence of diazoxide on regional blood flow in rats. Experientia 24, 242–243 (1968). https://doi.org/10.1007/BF02152793

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