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Inhibition of steroidΔ 4 reductase by heparin: Studies with desoxycorticosterone, progesterone, androstenedione and testosterone

  • Specialia
  • Chimica. Biochimica. Biophysica
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Zusammenfassung

Heparin hemmt die Reduktion der Doppelbindung in 4-Stellung des Rings A einer Reihe von C-11-desoxy,Δ 4-4-keto-Steroiden in der Rattenleber. Es scheint, dass Heparin mit NADPH um das Steroid-reduktase-Apoenzym konkurriert.

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References

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Authors and Affiliations

  1. Division of Clinical Pharmacology, University of Tennessee, Medical Units, 38103, Memphis, Tennessee, USA

    Patricia T. Krzanowski & R. C. Troop

Authors
  1. Patricia T. Krzanowski
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  2. R. C. Troop
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Additional information

This work was supported by grant No. AM-09151 from The National Institutes of Health, U.S.P.H.S.

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Krzanowski, P.T., Troop, R.C. Inhibition of steroidΔ 4 reductase by heparin: Studies with desoxycorticosterone, progesterone, androstenedione and testosterone. Experientia 24, 225–226 (1968). https://doi.org/10.1007/BF02152782

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  • DOI: https://doi.org/10.1007/BF02152782

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