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Experientia

, Volume 20, Issue 5, pp 279–280 | Cite as

Der Einfluss von Acetylcholin auf den Calciumumsatz ruhender und kontrahierender Vorhofmuskulaturin vitro

  • H. Hoditz
  • H. Lüllmann
Kurze Mitteilungen

Summary

Acetylcholine 5 × 10−8 g/ml reduces the Ca45 uptake of the beating left atria of guinea-pig; the tissue calcium is not altered. In resting atria, acetylcholine 5 × 10−7 g/ml has no influence upon the calcium content and Ca45 uptake. It is concluded that acetylcholine acts by shortening the action potential duration and thereby reduces the release of cellular calcium per excitation.

Literatur

  1. 1.
    H. Hoditz undH. Lüllmann, Pflügers Arch. ges. Physiol., im Druck.Google Scholar
  2. 2.
    W. Trautwein, Pharmacol. Rev.15, 277 (1963).Google Scholar

Copyright information

© Birkhäuser Verlag 1964

Authors and Affiliations

  • H. Hoditz
    • 1
  • H. Lüllmann
    • 1
  1. 1.Pharmakologisches Institut der Universität MainzDeutschland

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