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Über die Wirkung von synthetischem ACTH (β1–24Corticotropin) beim Menschen

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Summary

Syntheticβ 1–24Corticotropin (CIBA 30920-Ba) administered intravenously over 8 h to humans produced a significant rise in free plasma 17-hydroxycorticoids, urinary 17-hydroxycorticoids and 17-ketosteroids. The logarithmic dose response curve of the urinary 17-hydroxycorticoids was linear from 3 to 25 units. The comparison of the steroidogenic effect of the synthetic and natural ACTH (Cortrophin) revealed a more rapid but less sustained activity of the synthetic product.

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Authors and Affiliations

  1. Medizinische Universitätsklinik Basel, Schweiz

    A. Walser & F. Koller

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  1. A. Walser
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  2. F. Koller
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Walser, A., Koller, F. Über die Wirkung von synthetischem ACTH (β1–24Corticotropin) beim Menschen. Experientia 19, 320–322 (1963). https://doi.org/10.1007/BF02150434

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  • DOI: https://doi.org/10.1007/BF02150434

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