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Über eine mangelnde Parallelität zwischen Ionenpumpenhemmung und Kontraktionskraftsteigerung

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Summary

Δ 5-Pregnen-3,20-dione-N,N'-ethylpyrrolidine-bisguanylhydrazone and Δ5-pregnen-3β-hydroxy-20-one-N,N'-ethyl-pyrrolidine-monoguanylhydrazone inhibit the activity of the ionic pump of cold-stored erythrocytes of guinea-pigs. The contractile force of isolated guinea-pig auricles is decreased by the mono-derivate and increased by the bis-derivate in spite of the similar action upon the pumping mechanism.

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Authors and Affiliations

  1. Pharmakologisches Institut der Universität Mainz, Deutschland

    G. Kuschinsky, H. Lüllmann & U. Wollert

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  1. G. Kuschinsky
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  2. H. Lüllmann
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  3. U. Wollert
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Kuschinsky, G., Lüllmann, H. & Wollert, U. Über eine mangelnde Parallelität zwischen Ionenpumpenhemmung und Kontraktionskraftsteigerung. Experientia 20, 565–566 (1964). https://doi.org/10.1007/BF02150294

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  • DOI: https://doi.org/10.1007/BF02150294

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