, Volume 6, Issue 11, pp 422–423 | Cite as

Schädigung und sphärische Umwandlung der Erythrozyten bei der Hämagglutination

  • J. Tomcsik
  • C. A. Schild
Kurze Mitteilungen


The sheep erythrocyte antibodies produced in rabbits cause a marked deformity and a fusion of the red blood cells during their agglutination. These changes could be eliminated if albumin (antispherical factor) or lecithin (spherical factor) was added to the agglutinating serum. On the contrary several hemagglutinating sera obtained from human infectious mononucleosis cases do not cause any deformities of the sheep blood cells; they contain in surplus a spherical factor.

The general conception that the hemagglutinins induce invariably a deformation of the agglutinated red cells can not be maintained. The balance of a spherical and of an antispherical factor is more important in the production of red cell deformities than the antibodies themselves.


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Copyright information

© Birkhäuser Verlag 1950

Authors and Affiliations

  • J. Tomcsik
    • 1
  • C. A. Schild
    • 1
  1. 1.Hygiene-Institut der Universität BaselSwitzerland

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