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Über biologische Wirkungen von Acridinderivaten

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Summary

The A.D. Atebrin, Rivanol, Nitroacridin No. 3582 have a spasmolytic effect on the spontaneous activity of the isolated ileum of the guinea pig, also on contractions caused by histamine, acetylcholine BaCl2 and sensibilating protein.

The histamine suppressing effect of Rivanol and Atebrin is larger than that of acetylcholine.

The A.D. accelerate in concentrations of 10−6−10−5 the chronotropy and raise the inotropy, if the latter are decreased by acetylcholine or KCl.

The efficiency of A.D. on the isolated ileum and the isolated heart are compared with that of atropine, adrenalin, and antistin.

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References

  1. E. Lenz, Z. ges. exp. Med.12, 195 (1921).

    Article  CAS  Google Scholar 

  2. G. Monasterio, Arch. exp. Path. und Pharm.159, 172 (1931).

    Article  CAS  Google Scholar 

  3. L. Benda, Med und Chem.1, 51 (1933) Bayer Leverkusen.

    Google Scholar 

  4. R. Schnitzer, Med. und Chem.3, 34 (1936) Bayer Leverkusen.

    CAS  Google Scholar 

  5. Nonnenbruch undWenzel, Ref. in Klin. Wschr.11, 485 (1932).

    Google Scholar 

  6. J. Wagner-Jauregg, Naturwissenschaften31, 335 (1943).

    Article  CAS  Google Scholar 

  7. F. Peter, Münch. med. Wschr.74, 1709 (1927).

    Google Scholar 

  8. O. Wagner, Beiheft Schiffs- und Tropenhyg.32, 159 (1928).

    Google Scholar 

  9. F. Eichholz,Lehrbuch der Pharmakologie (Berlin, Springer 1944, S. 503).

    Book  Google Scholar 

  10. K. Umrath, mündliche Mitteilung.

  11. O. Schaumann, Beiheft Arch. Schiffs- und Tropenhyg.32, 170 (1928).

    Google Scholar 

  12. A. Heathcote undA. L. Urquart, J. Pharm. exp. Ther.38, 145 (1930).

    CAS  Google Scholar 

  13. J. Janner, Schweiz. Z. Path. und Bakt.11, 289 (1948).

    CAS  Google Scholar 

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Müssbichler, H. Über biologische Wirkungen von Acridinderivaten. Experientia 7, 185–186 (1951). https://doi.org/10.1007/BF02148908

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