Abstract
A report is given of an outbreak of respiratory syncytial virus infection in a neonatal unit in France. Twenty-three of 32 infants were infected (72 %) despite infection control procedures. Prophylactic administration of non-specific gamma globulins was associated with a significant decrease in infection rate (p < 0.05). The administration of transfer factor to infected infants was also associated with a significantly lower rate of severe respiratory diseases (p < 0.05).
Similar content being viewed by others
References
Hall, C. B., Kopelman, A. E., Douglas, R. G., Geiman, J. M., Meagher, M. P.: Neonatal respiratory syncytial virus infection. New England Journal of Medicine 1979, 300: 393–396.
Pothier, P., Nicolas, J. C., Prudhomme de Saint Maur, G., Ghim, S., Kazmierczac, A., Bricout, F.: Monoclonal antibodies against respiratory syncytial virus and their use for rapid detection in nasopharyngeal secretions. Journal of Microbiology 1985, 12: 286–287.
Hall, C. B.: The nosocomial spread of respiratory syncytial viral infections. Annual Review of Medicine 1983, 34: 311–319.
Ogilvie, M. M., Vathenen, A. S., Radford, M., Godd, J., Key, S.: Maternal antibody and respiratory syncytial virus infection in infancy. Journal of Medical Virology 1981, 7: 263–271.
Hemming, V. G., Weisman, L. E., Prince, G. A., Horswood, R. L., Fischer, G. W.: Respiratory syncytial virus (rsv) neutralizing antibody titers in human immune serum globulin for intravenous (IVIG) infusion. Pediatric Research 1984, 18: 277A.
Prince, G. A., Hemming, V. G., Horswood, R. L., Murphy, B. R., Chanock, R. M.: Intravenous serum globulin (IVIG) for prophylaxis and treatment of respiratory syncytial virus (rsv) infection in cotton rat. Pediatric Research 1984, 18: 284A.
Thomas, I. T., Hawkins, G. T., Soothil, J. F., Marshall, W. C.: Transfer factor treatment in congenital cytomegalovirus infection. Lancet 1977, ii: 1056–1057.
Kahn, A.: Transfer factor in viral diseases. Lancet 1978, ii: 328–329.
Gardner, P. S., McGuckin, R., Beale, A. J., Fernandes, R.: Interferon and respiratory syncytial virus. Lancet 1970, i: 574–575.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Gouyon, J.B., Pothier, P., Guignier, F. et al. Outbreak of respiratory syncytial virus in France. Eur. J, Clin. Microbiol. 4, 415–416 (1985). https://doi.org/10.1007/BF02148696
Issue Date:
DOI: https://doi.org/10.1007/BF02148696