Skip to main content
SpringerLink
Log in

Pharmacological studies with some new antihypertensive aminoquinazolines

  • Specialia
  • Pharmacologica
  • Published:
Experientia Aims and scope Submit manuscript

Zusammenfassung

4 neue Aminoquinazolin-Derivate, die den Blutdruck von Hunden und Katzen herabsetzen, werden beschrieben. Ihre wirksamen Dosen liegen im Bereiche von 20 bis 300µg/kg peroral. Diese Substanzen setzen den peripheren Widerstand herab und reduzieren die blutdrucksteigernde Wirkung von Adrenalin, unterscheiden sich aber von den typischenα-Sympatholytika.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Literatur

  1. H.-J. Hess, T. H. Cronin andA. Scriabine, J. med. Chem.11, 130 (1968).

    Article  CAS  Google Scholar 

  2. H. Goldblatt, J. Lynch, R. F. Hanzal andW. W. Summerville, J. exp. Med.59, 347 (1934).

    Article  CAS  Google Scholar 

  3. N. A. Prioli andM. M. Winbury, J. appl. Physiol.15, 323 (1960).

    Article  CAS  Google Scholar 

  4. W. F. Hamilton, J. W. Moore, J. M. Kinsman andR. G. Spurling, Am. J. Physiol.99, 534 (1932).

    Article  CAS  Google Scholar 

  5. H. D. Green, R. N. Lewis, N. D. Nickerson andA. L. Heller, Am. J. Physiol.141, 518 (1944).

    Article  Google Scholar 

  6. W. Halleck, J. appl. Physiol.22, 593 (1967).

    Article  CAS  Google Scholar 

  7. J. W. Constantine, W. K. McShane, A. Scriabine andH.-J. Hess, in preparation.

Download references

Author information

Author notes

  1. A. Scriabine

    Present address: Merek Institute for Therapeutic Research, 19486, West Point, Pennsylvania, USA

Authors and Affiliations

  1. Department of Pharmacology, Medical Research Laboratories, Chas. Pfizer & Co., Inc., 06340, Groton, Conn., USA

    A. Scriabine, J. W. Constantine, H. -J. Hess & W. K. McShane

Authors
  1. A. Scriabine
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. J. W. Constantine
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. H. -J. Hess
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. W. K. McShane
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Scriabine, A., Constantine, J.W., Hess, H.J. et al. Pharmacological studies with some new antihypertensive aminoquinazolines. Experientia 24, 1150–1151 (1968). https://doi.org/10.1007/BF02147820

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02147820

Keywords

Search

Navigation