Experientia

, Volume 27, Issue 5, pp 570–571 | Cite as

Interaction of specific antibody precursor cells in vitro with a bacterial somatic antigen

  • H. Friedman
Specialia Haematologica, Immanologica
  • 5 Downloads

Keywords

Specific Antibody Precursor Cell Somatic Antigen Antibody Precursor 

Zusammenfassung

Es gelingt durch niedertourige Differentialzentrifugierung normaler Milzzellen der Maus, in vitro mitE.-coli-Suspensionen inkubiert, den Grobteil der Vorläufer Antikörper bildender Zellen abzutrennen, welche zusammen mitE. coli spezifische Agglutinine bilden konnten. Dies war durch Erfassung bakterieller «Kolonieverklumpung» in Empfänger-Mäusen zu bestimmen.

Literatur

  1. 1.
    J. C. Gowans andD. D. McGregor, Progr. Allergy9, 1 (1965).Google Scholar
  2. 2.
    N. A. Mitchison, Cold Spring Harbor Symp. quant. Biol.32, 431 (1967).Google Scholar
  3. 3.
    D. Naor andD. Sulitzeanu, Nature, Lond.208, 500 (1965).Google Scholar
  4. 4.
    D. Naor andD. Sulitzeanu, Nature, Lond.214, 687 (1967).Google Scholar
  5. 5.
    G. L. Ada andP. Byrt, Nature, Lond.222, 1291 (1969).Google Scholar
  6. 6.
    P. Byrt andG. L. Ada, Immunology17, 503 (1969).PubMedGoogle Scholar
  7. 7.
    N. L. Warner, P. Byrt andG. L. Ada, Nature, Lond.226, 942 (1970).Google Scholar
  8. 8.
    J. Humphrey andH. V. Keller, inDevelopmental Aspects of Antibody Formation and Structure (Eds.J. Sterzl andM. Riha; Academic Press, New York 1970), in press.Google Scholar
  9. 9.
    S. A. Schwartz andW. Braun, Science149, 200 (1965).Google Scholar
  10. 10.
    M. Landy, R. P. Sanderson andA. L. Jackson, J. exp. Med.122, 483 (1965).CrossRefPubMedGoogle Scholar
  11. 11.
    P. J. Baker, H. Bernstein, V. Pasanen andM. Landy, J. Immun.97, 767 (1966).PubMedGoogle Scholar
  12. 12.
    G. Biozzi, C. Stiffel, D. Monton, Y. Bouthillier andC. Decreusefond, Immunology14, 7 (1968).PubMedGoogle Scholar
  13. 13.
    G. M. Shearer andG. Cudkowicz, J. Immun.101, 1263 (1968).Google Scholar
  14. 14.
    H. Friedman, J. Allen andJ. Rosenzweig, Proc. Soc. exp. Biol. Med.131, 353 (1969).PubMedGoogle Scholar
  15. 15.
    O. B. Zaalberg, V. A. van der Meul andT. van Twisk, Nature, Lond.210, 544 (1966).Google Scholar
  16. 16.
    J. H. L. Playfair, B. W. Papermaster andL. J. Cole, Science149, 998 (1965).PubMedGoogle Scholar
  17. 17.
    J. C. Kennedy, J. E. Till, L. Siminowitch andE. A. McCulloch, J. Immun.96, 973 (1966).PubMedGoogle Scholar
  18. 18.
    W. D. Armstrong andE. Diener, J. exp. Med.129, 371 (1969).CrossRefPubMedGoogle Scholar
  19. 19.
    G. M. Shearer, G. Cudkowicz andR. L. Priore, J. exp. Med.129, 185 (1969).CrossRefPubMedGoogle Scholar
  20. 20.
    H. Friedman, J. Allen andM. Landy, J. Immun.103, 204 (1969).PubMedGoogle Scholar
  21. 21.
    H. Friedman andM. Landy, Cell Immun., submitted (1970).Google Scholar

Copyright information

© Birkhäuser Verlag 1971

Authors and Affiliations

  • H. Friedman
    • 1
  1. 1.Department of MicrobiologyAlbert Einstein Medical CenterPhiladelphiaUSA

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