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Species differences in the influence of chlorothiazide on curarization

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  • Pharmacologica
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Résumé

Chez le Chien, le Chat, le Cobaye et le Rat, le chlorothiazide est antagoniste de lad-tubocurarine. Chez le Lapin, le chlorothiazide potentialise la paralysied-tubocurarinique, mais exerce une action antagoniste vis-à-vis d'autres curarimimétiques. L'administration préalable de phénylbutazone transforme en antagonisme la synergie entre le chlorothiazide et lad-tubocurarine.

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Authors and Affiliations

  1. Department of Pharmacology and Experimental Therapeutics, Instituto de Ciencias Biologicas, UFRJ, Rio de Janeiro, Brasil

    G. Suarez-Kurtz (Fellows of the Conselho Nacional de Pesquisas) & L. G. Paul (Fellows of the Conselho Nacional de Pesquisas)

  2. Departamento de Farmacologia e Terapeutica Experimental, 458 av. Pasteur, Rio de Janeiro, Brasil

    G. Suarez-Kurtz (Fellows of the Conselho Nacional de Pesquisas)

Authors
  1. G. Suarez-Kurtz
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  2. L. G. Paul
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Suarez-Kurtz, G., Paul, L.G. Species differences in the influence of chlorothiazide on curarization. Experientia 27, 539–541 (1971). https://doi.org/10.1007/BF02147587

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  • DOI: https://doi.org/10.1007/BF02147587

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