Experientia

, Volume 23, Issue 10, pp 853–855 | Cite as

Presence of calcium ions as a requisite for the in vitro stimulation of TSH-release by hypothalamic TRF

  • W. Vale
  • R. Burgus
  • R. Guillemin
Specialia Endocrinologica

Keywords

Calcium Facteur Hypothalamique 

Résumé

L'incubation in vitro de fragments d'hypophyse (rat) dans le liquide de Krebs-Ringer sans calcium (Ca++) inhibe l'action du facteur hypothalamique TRF (TSH-releasing factor) qui normalement stimule la sécrétion de l'hormone thyréotrope (TSH). La ré-introduction de l'ion Ca++ (2.54 mM) rétablit la réponse (sécrétion de TSH) au facteur TRF.

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Copyright information

© Birkhäuser Verlag 1967

Authors and Affiliations

  • W. Vale
    • 1
  • R. Burgus
    • 1
  • R. Guillemin
    • 1
  1. 1.Department of PhysiologyBaylor University College of Medicine HoustonUSA

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