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The intermediate role of 18-hydroxycorticosteroids in aldosterone biosynthesis

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  • Chimica. Biochimica. Biophysica
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Zusammenfassung

Durch ihre Eigenschaft, bestimmte Stufen bei der Bildung radioaktiv markierten Aldosterons aus14C-Progesteron bzw.3H-11-Desoxycorticosteron zu hemmen, erwiesen sich 11-Desoxycorticosteron, Corticosteron und 18-Hydroxycorticosteron als wesentliche Zwischenstufen der Aldosteronbiosynthese. 18-Hydroxy-11-desoxycorticosteron hingegen scheint an der Bildung von Aldosteron nicht beteiligt zu sein.

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Authors and Affiliations

  1. I. Medizinische Klinik und Poliklinik der Johannes-Gutenberg-Universität, 6500, Mainz, Germany

    P. Vecsei, D. Lommer & H. P. Wolff

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  1. P. Vecsei
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  2. D. Lommer
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  3. H. P. Wolff
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Vecsei, P., Lommer, D. & Wolff, H.P. The intermediate role of 18-hydroxycorticosteroids in aldosterone biosynthesis. Experientia 24, 1199–1201 (1968). https://doi.org/10.1007/BF02146618

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  • DOI: https://doi.org/10.1007/BF02146618

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