Skip to main content
SpringerLink
Log in

Uptake of some amino acids by rat brain slices: Effect of various substrates

  • Specialia
  • Chimica. Biochimica. Biophysica
  • Published:
Experientia Aims and scope Submit manuscript

Résumé

En milieu de Krebs-Ringer oxygéné et glucosé, les coupes de cortex cérébral de Rat accumulent les acides aminés contre un gradient de concentration. L'anoxie, l'exclusion du substrat, et les inhibiteurs métaboliques inhibent cette accumulation. Parmi les substrats de la chaîne glycolytique et du cycle de Krebs étudiés, le succinate et le fumarate donnent les niveaux d'accumulation les plus réduits. On observe très généralement une corrélation entre la teneur des composés phosphorylés riches en énergie, et l'accumulation active des acides aminés.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Literatur

  1. J. R. Stern, L. V. Eggleston, R. Hems andH. A. Krebs, Biochem. J.44, 410 (1949).

    Article  CAS  Google Scholar 

  2. P. N. Abadom andP. G. Scholefield, Can. J. Biochem.40, 1575 (1962).

    CAS  Google Scholar 

  3. K. D. Neame, J. Neurochem.11, 67 (1964).

    Article  CAS  Google Scholar 

  4. S. Lahiri andA. Lajtha, J. Neurochem.11, 77 (1964).

    Article  CAS  Google Scholar 

  5. R. Blasberg andA. Lajtha, Brain Res.1, 86 (1966).

    Article  CAS  Google Scholar 

  6. H. McIlwain andP. Joanny, J. Neurochem.10, 313 (1963).

    Article  Google Scholar 

  7. C. Dumazert andR. Grangaud, Soc. Pharmac., Montpellier1, 17 (1954).

    Google Scholar 

  8. H. T. McPherson, Biochem. J.40, 470 (1946).

    Article  Google Scholar 

  9. C. Dumazert andR. Poggi, Bull. Soc. Chim. biol.21, 1381 (1939).

    CAS  Google Scholar 

  10. F. P. Chinard, J. biol. Chem.199, 91 (1952).

    Article  CAS  Google Scholar 

  11. G. A. Bray, Anal. Biochem.1, 279 (1960).

    Article  CAS  Google Scholar 

  12. P. Joanny andE. Barbosa, J. Physiol., Paris, in press (1968).

  13. H. McIlwain,Biochemistry and the Central Nervous System (Churchill, London 1959).

    Google Scholar 

  14. P. Joanny andH. Hillman, J. Neurochem.10, 655 (1963).

    Article  CAS  Google Scholar 

  15. R. J. Woodman andH. McIlwain, Biochem. J.81, 83 (1961).

    Article  CAS  Google Scholar 

  16. H. McIlwain, L. Buchel andJ. Cheshire, Biochem. J.48, 12 (1951).

    Article  CAS  Google Scholar 

  17. H. McIlwain, Biochem. J.52, 289 (1952).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Laboratoire de Physiologie, Faculté de Médecine, Marseille 5e, France

    E. Barbosa, P. Joanny & J. Corriol

Authors
  1. E. Barbosa
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. P. Joanny
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. J. Corriol
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Barbosa, E., Joanny, P. & Corriol, J. Uptake of some amino acids by rat brain slices: Effect of various substrates. Experientia 24, 1196–1197 (1968). https://doi.org/10.1007/BF02146616

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02146616

Keywords

Search

Navigation