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Der Einfluss der experimentellen Leberschädigung auf Gesamtfett und ungesättigte Fettsäuren in Serum und Leber

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Summary

In experiments on rats with CCl4-induced liver damage the total lipids and the di- to tetra-enoic fatty acids were estimated. The acute experiment of 72 h duration showed a strong augmentation of total lipids and a transitory diminution of arachidonic acid in serum and liver which two months after the intoxication still persisted together with a marked rise in linolenic acid. The parallelism of changes of saturation of the fatty acids in serum and liver being statistically significant indicates that the process of desaturation is most probably localized in the liver itself.

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References

  1. K. R. Rees, Ciba Foundation Symposium:Enzymes and Drugs Action (1961), p. 344.

  2. W. R. Bloor, K. F. Pelkan undP. M. Allen, J. biol. Chem.52, 201 (1922).

    Article  Google Scholar 

  3. S. F. Herb undR. W. Riemenschneider, Analyt. Chem.25, 953 (1953).

    Article  CAS  Google Scholar 

  4. W. Schrade, R. Biegler undC. Ott, Klin. Wschr.34, 1242 (1956).

    Article  CAS  Google Scholar 

  5. J. Schmidt-Thomé undH. Augustin, Z. physiol. Chem.275, 190 (1942).

    Article  Google Scholar 

  6. M. M. Nothman undS. Proger, Fed. Proc.19, 221 (1960).

    Google Scholar 

  7. Die Untersuchungen wurden durch ein Forschungsstipendium der Ciba ermöglicht. Die Cholesterinbestimmungen wurden in den Ciba-Laboratorien (Prof.Schuler, Dr.Albrecht) ausgeführt. Frl.M. Schluchter bin ich für die sorgfältigen übrigen Bestimmungen zu grösstem Dank verpflichtet.

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Authors and Affiliations

  1. Medizinische Poliklinik Basel, Schweiz

    S. Markees

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  1. S. Markees
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Markees, S. Der Einfluss der experimentellen Leberschädigung auf Gesamtfett und ungesättigte Fettsäuren in Serum und Leber. Experientia 20, 50–54 (1964). https://doi.org/10.1007/BF02146042

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  • DOI: https://doi.org/10.1007/BF02146042

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