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l-DOPA administration to neonate chicks: Effects on behavior and levels of brain biogenic amines

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Zusammenfassung

Nachweis, dass bei Küken die i.v. Injektion vonl-Dopa (100 mg/kg) eine sofortige Überaktivität herbeiführt. Nach 10 min wurde im Gehirn eine Verminderung des Serotoningehaltes (14%) und eine Erhöhung des Dopamingehaltes (12fach) festgestellt, während Adrenalin, Noradrenalin und Histamin unverändert blieben.

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Author notes

  1. J. P. Hanig

    Present address: Food and Drug Administration, Bureau of Drugs, Division of Drug Biology BD-413, 20204, Washington, D.C., N.Y., USA

Authors and Affiliations

  1. Department of Pharmacology, New York Medical College, Flower-Fifth Avenue Hospitals, 10029, New York, N.Y., USA

    J. P. Hanig & J. Seifter

Authors
  1. J. P. Hanig
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  2. J. Seifter
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Additional information

The author (JPH) was supported in part by a National Science Foundation Predoctoral Traineeship.

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Hanig, J.P., Seifter, J. l-DOPA administration to neonate chicks: Effects on behavior and levels of brain biogenic amines. Experientia 27, 168–169 (1971). https://doi.org/10.1007/BF02145875

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