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Isolation and structure of bombesin and alytesin, two analogous active peptides from the skin of the european amphibiansBombina andAlytes

Experientia volume 27, pages 166–167 (1971)Cite this article

Riassunto

Viene descritto l'isolamento e il chiarimento della struttura della bombesina e della alytesina due tetradecapeptidi attivi a struttura analoga presenti nella pelle fresca rispettivamente dellaBombina e dell'Alytes, anfibi europei della famiglia dei discoglossidi. I due polipeptidi manifestano azioni farmacologiche similari sulla pressione del sangue, su svariati organi a muscoli lisci, sulla secrezione gastrica e sulla glicemia.

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References

  1. V. Erspamer, G. Falconieri Erspamer andM. Inselvini, J. Pharm. Pharmac., in press.

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Authors and Affiliations

  1. Istituto di Ricerca di Base, Farmitalia S.p.A., Milano e Istituto di Farmacologia medica, Università di Roma, Italy

    A. Anastasi, V. Erspamer & M. Bucci

Authors
  1. A. Anastasi
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  2. V. Erspamer
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  3. M. Bucci
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Additional information

In part supported by grants from the Consiglio Nazionale delle Ricerche, Rome.

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Anastasi, A., Erspamer, V. & Bucci, M. Isolation and structure of bombesin and alytesin, two analogous active peptides from the skin of the european amphibiansBombina andAlytes. Experientia 27, 166–167 (1971). https://doi.org/10.1007/BF02145873

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  • DOI: https://doi.org/10.1007/BF02145873

Keywords

  • Glucose Unit
  • Bombesin
  • Dansyl
  • Paper Electrophoresis
  • Dinitrophenyl