Summary
Testsin vitro with a number of strains of human typeMycobacterium tuberculosis have shown that they habituate much more to streptomycin than to PAS. Up-to-date no true PAS resistance could be obtained.
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Literatur
R. J. Dubos, Exper.3, 45 (1947).
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Hurni, H. Gibt es eine Gewöhnung an p-Aminosalicylsäure (PAS)?. Experientia 5, 128 (1949). https://doi.org/10.1007/BF02145310
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DOI: https://doi.org/10.1007/BF02145310