Summary
Treatment of gramicidin with ozone in formic acid leads to a tryptophan-N'-formylkynurenine conversion. Such a conversion causes a decrease of both bacteriostatic and haemolytic activities.
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Galzigna, L., Previero, A., Reggiani, A. et al. Inattivazione della gramicidina dovuta alla conversione triptofano → N'-Formilchinurenina. Experientia 20, 669–670 (1964). https://doi.org/10.1007/BF02145260
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DOI: https://doi.org/10.1007/BF02145260