Summary
The authors have tried to observe, with the aid of the electron microscope, the effect of streptomycin on the morphology ofB. subtilis. This action is very swift and manifests itself by the appearance of cells with high turgescence (“sporical” forms, but not resistant), by extreme shrinkage of cytoplasm inside the cell-wall and by the extrusion of this cytoplasm from the cellular envelope.
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Kellenberger, E., Werner, G.H. L'action antibiotique de la streptomycine étudiée au microscope électronique. Experientia 4, 440–441 (1948). https://doi.org/10.1007/BF02145001
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DOI: https://doi.org/10.1007/BF02145001