Summary
When rabbit muscles are fatigued, the electrophoretic pictures of the extracts of these muscles are free from α-myosin and show a large decrease in the amount of β1 and β2-myosin.
When the muscles are contracted by monobromacetate or stimulated and fixed in a contracted state by liquid air, α-myosin is very much decreased, β1 and β2-myosin disappears entirely, and a new component appears which is called “contractin”.
The disappearance of the classical myosins and the appearance of this new protein in the extracts ofshortened muscles, may be of great interest in the study of the protein changes responsible for muscle contraction.
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Dubuisson, M. Apparition d'une protéine nouvelle, la contractine, dans les extraits de muscles contractés. Experientia 4, 437–440 (1948). https://doi.org/10.1007/BF02145000
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DOI: https://doi.org/10.1007/BF02145000