Summary
This preliminary communication describes red, watersoluble pigments elaborated by an adeninedeficient mutant of a haploid strain of yeast (Saccharomyces cerevisiœ). Acid hydrolysis of these pigments liberates a number of amino acids. Some of the physical and chemical properties of these yeast pigments resemble those of the antipernicious anæmia factor (vitamin B12 1) which contains one atom of cobalt and three atoms of phosphorus, with a molecular weight of 1,500. Our yeast pigments contain no cobalt but one or two atoms of phosphorus, with an approximate molecular weight of 2,000.
A report on the biological activities of our pigments will appear in the near future.
Literatur
E. Lederer, C. R. Acad. Sci.197, 1694 (1933); Bull. Soc. Chim. biol.20, 611 (1938).
H. Fink etE. Zenger, Wschr. Brauerei1934, No 12.
Cl. Fromageot etJ. L. Tchang, Arch. Mikrobiol.9, 424 et 434 (1938).
P. Karrer etJ. Rutschmann, Helv. chim. acta26, 2109 (1943);28, 795 (1945);29, 355 (1946).
E. Tavlitzki, communication verbale.
R. Consden, A. H. Gordon etA. J. P. Martin, Biochem. J.38, 224 (1944).
Analyse deM. Justisz.
E. L. Rickes, N. G. Brink, F. R. Koniuszy, T. R. Wood etK. Folkers, Science107, 396 (1948).
E. Lester Smith, Nature161, 638 (1948).
M. S. Shorb, J. Biol. Chem.169, 455 (1947); Science107, 397 (1948).
Nous remercions le ProfesseurT. Reichstein, Bâle, qui a bien voulu comparer quelques-unes de nos fractions avec des pigments extraits du foie.
Etant donné l'état amorphe de nos pigments, il n'est pas encore certain que les acides aminés décelés après hydrolyse fassent partie de ces pigments. La présence d'impuretés protéiques ou peptidiques n'est pas exclue.
Cf. notes 3 and 4 p. 433, 2nd column.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Ephrussi, B., Lederer, E. Sur des pigments rouges de Levures. Experientia 4, 433–434 (1948). https://doi.org/10.1007/BF02144997
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF02144997