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Histone acetylation in scrapie-affected mouse brain

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  • Chimica. Biochimica. Biophysica
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Zusammenfassung

Im Gehirn von Mäusen mit Traberkrankheit (Scrapie) war die Azetylierung von Histonen um 25% erhöht. Diese chemische Änderung erschien weitaus früher als klinische Symptome und histologisch-pathologische Veränderungen. Die Beziehung von Azetyl-Histonen zu Deoxyribonukleinsäuren und ihre Verhältnisse zur Aktivierung von spezifischen Nervenzellen werden kurz besprochen.

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Authors and Affiliations

  1. Medical Research Council, Demyelinating Diseases Research Unit, Newcastle upon Tyne 2, England

    E. A. Caspary & Frances M. Sewell

Authors
  1. E. A. Caspary
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  2. Frances M. Sewell
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Caspary, E.A., Sewell, F.M. Histone acetylation in scrapie-affected mouse brain. Experientia 24, 793–794 (1968). https://doi.org/10.1007/BF02144871

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  • DOI: https://doi.org/10.1007/BF02144871

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