Zusammenfassung
Die sekundären Tetrahydroisochinoline Ia, b, c wurden mit Hilfe einer modifizierten Pictet-Spengler-Kondensation in die (±)-Homoberbine IIIa, b, c übergeführt. Diese Homoberbine stellen eine neue Klasse potentieller Alkaloide dar.
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Literatur
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Our proposed nomenclature for this ring system is: 5,6,8,13,14,14a-hexahydroisoquino[2,1-b][2]benzazepine.
M. J. H. is the recipient of N.I.H. predoctoral fellowship No. 5 Fl GM-32,921. M. S. wishes to acknowledge financial assistance through N.I.H. grant No. GM-10608.
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Brossi, A., Rachlin, A.I., Teitel, S. et al. (±)-Homoberbines, a new class of heterocyclic compounds. Experientia 24, 766 (1968). https://doi.org/10.1007/BF02144853
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DOI: https://doi.org/10.1007/BF02144853