Résumé
Les boutons terminaux des fibres moussues du cervelet ont été separés des petits boutons de la couche moléculaire après homogénéisation et fractionnement. La fusion intracytoplasmique des vésicules synaptiques se produisant sous l'effet de la chaleur indiquerait un mécanisme de libération du médiateur.
Literatur
V. P. Whittaker, Proc. Fourth Internat. Neurochem. Symp., Varenna, June 12–17 (1960), inRegional Neurochsmistry (Ed.S. Kety andJ. Elkes; Pergamon Press, Oxford), p. 259.
E. G. Gray andV. P. Whittaker, J. Physiol.153, 35 P (1960).
E. G. Gray andV. P. Whittaker, J. Anat., Lond.96, 79 (1962).
V. P. Whittaker, Progr. Biophys. mol. Biol.15, 39 (1964).
V. P. Whittaker, I. A. Michaelson, andR. J. A. Kirkland, Biochem. J.90, 293 (1964).
V. P. Whittaker, inSeparation of Subcellular Structural Components, Biochem. Soc. Symp. N. 23 (Ed.J. K. Grant; University Press, Cambridge 1963), p. 109.
E. G. Gray, J. Anat., Lond.95, 345 (1961).
R. L. Friede andL. M. Fleming, J. Neurochem.11, 1 (1964).
D. R. Curtis, J. M. Crawford, P. E. Voorhoeve, andV. J. Wilson, Nature, Lond.200, 579 (1963).
V. P. Whittaker, Biochem. J.72, 694 (1959).
Author information
Authors and Affiliations
Additional information
The work was supported by USPHS grant No. NB 03928-03 from the National Institute of Neurological Diseases and Blindness. The electron microscope was provided by the Wellcome Trust. The participation of Dr.M. N. Sheridan in the early stages of this work and the technical assistance of MissL. Swales are gratefully acknowledged.
Rights and permissions
About this article
Cite this article
Israël, M., Whittaker, V.P. The isolation of mossy fibre endings from the granular layer of the cerebellar cortex. Experientia 21, 325–326 (1965). https://doi.org/10.1007/BF02144693
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF02144693