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Effect of chronic ethanol treatment on peroxisomal acyl-CoA oxidase activity and lipid peroxidation in rat liver and heart

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Chronic ethanol administration was shown to increase catalase and acyl-CoA oxidase activities in rat myocardium but did not alter the activity of liver peroxisomal enzymes. As a result of alcohol consumption a 2–3-fold increase in the level of lipid peroxidation was observed in the heart tissue while in the liver the induction was much less pronounced.

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References

  1. Lazarow, P.B., and de Duve, Ch., Proc. natn. Acad. Sci. USA73 (1976) 2043.

    Article  CAS  Google Scholar 

  2. Norseth, J., and Thomassen, M.S., Biochim. biophys. Acta751 (1983) 312.

    Article  CAS  PubMed  Google Scholar 

  3. Fahimi, H.D., Kino, M., Hicks, L., Thorp, K.A., and Abelman, W.H., Am. J. Path.96 (1979) 373.

    CAS  PubMed  PubMed Central  Google Scholar 

  4. de Master, E.G., Kaplan, E., Chasler, E., Alcoholism: clin. exp. Res.5 (1981) 45.

    Article  Google Scholar 

  5. Panchenko, L.F., Antonenkov, V.D., and Gerasimov, A.M., Int. J. Biochem.7 (1976) 409.

    Article  CAS  Google Scholar 

  6. Panchenko, L.F., Pirozhkov, S.V., and Antonenkov, V.D., Biochem. Pharmac.34 (1985) 471.

    Article  CAS  Google Scholar 

  7. Lieber, C.S., Jones, D.F., and de Carli, L.M., J. clin. Invest.44 (1965) 1009.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Horie, S., Ishii, H., and Suga, T., Life Sci.29 (1981) 1649.

    Article  CAS  PubMed  Google Scholar 

  9. Beers, R.F., and Sizer, J.W., J. biol. Chem.195 (1952) 133.

    Article  CAS  PubMed  Google Scholar 

  10. Leighton, F., Poole, B., Beaufay, H., Baudhuin, P., Coffey, J.W., Fowler, St., and de Duve, Ch., J. Cell Biol.37 (1968) 482.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  11. Hayashi, H., Suga T., and Niinobe, S., Biochim. biophys. Acta252 (1971) 58.

    Article  CAS  PubMed  Google Scholar 

  12. Ernster, L., and Nordenbrand, K., in: Methods in Enzymology, vol. 10, p. 574. Academic Press, New York 1967.

    Google Scholar 

  13. Trush, M.A., Wilson, M.E., and Van Dyke, K., in: Methods in Enzymology, vol. 57, p. 462, Academic Press, New York 1978.

    Google Scholar 

  14. Lowry, O.H., Rosebrough, N.J., Farr, A.L., and Randall, R.J., J. biol. Chem.193 (1951) 265.

    Article  CAS  PubMed  Google Scholar 

  15. Chance, B., Sies, H., and Boveris, A., Physiol. Rev.59 (1979) 527.

    Article  CAS  PubMed  Google Scholar 

  16. Schreiber, S.S., Oratz, M., Rothschild, M.A., Reff, F., and Evans, C., J. molec. cell. Cardiol.6 (1974) 207.

    Article  CAS  Google Scholar 

  17. Kupary, M., Lindros, K., Hillbom, M., Heikkila, J., and Ylikahri, R., Alcoholism: clin. exp. Res.7 (1983) 283.

    Article  Google Scholar 

  18. Dianzani, M.U., Alcohol Alcoholism20 (1985) 161.

    CAS  PubMed  Google Scholar 

  19. Cadenas, E., and Sies, H., Adv. Enzyme Regul.23 (1985) 217.

    Article  CAS  PubMed  Google Scholar 

  20. Kino, M., J. molec. cell. Cardiol.13 (1981) 5.

    Article  CAS  Google Scholar 

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Panchenko, L.F., Pirozhkov, S.V., Popova, S.V. et al. Effect of chronic ethanol treatment on peroxisomal acyl-CoA oxidase activity and lipid peroxidation in rat liver and heart. Experientia 43, 580–581 (1987). https://doi.org/10.1007/BF02143593

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